Reactions in the Slime

Legionella - Nanoparticles

Bacteria internalizing particles? It would seem so. In the first two boxes below we see the bioaccumulation of gold nanoparticles (in red in B) on Legionella biofilms. In (d), Legionella bacteria were incubated overnight with gold nanoparticles and then sectioned and imaged by electron microscopy demonstrating the presence of gold containing clusters inside of bacteria that are not seen in controls (c) . So, how are the bacteria sensing, responding and possibly taking up nanomaterials - this is what we're trying to find out! We're currently investigating a set of genes that may be involved in a unique metal sensing and detoxification system.